Target Discovery
Speed to Discovery.
For the first time in human history, we can study human cancers in their native microenvironments:
- Breast cancer in human breast tissue
- Prostate cancer in human periprostatic fat
- Colon cancer in human pericolonic fat
- Peritoneal metastases in human peritoneal fat (e.g. mesentery, omentum)
Kelion Technology unlocks the in vivo phenotypes of these human cancers. For example:
- Lipid-driven metabolism and metabolic reprogramming
- Dynamic, complex interactions between cancer and immune cells, stromal cells, perivascular cells, stem cells
- Cancer-driven remodeling of the tumor microenvironment, including the fully intact extracellular matrix
- Cancer, immune system, microbiome interactions
We offer the full breadth of experimental customization. Clients can select:
- Demographics and medical comorbidities of tissue donors
- Cancer models from cell lines to organoids/spheroids, to patient-derived xenografts
- Duration of experiments; our models are stable for at least 8 weeks in culture
